Systematic Review Club

Review 1 Lead: Dr Lemma Bulto

1.       Effectiveness of nurse-led interventions versus usual care to optimise blood pressure management and lifestyle behaviour modification in patients with primary hypertension: a systematic review protocol 2021 CRD42021274900

2.       Bulto LN, Roseleur J, Noonan S, Pinero de Plaza MA, Champion S, Dafny HA, Pearson V, Nesbitt K, Gebremichael LG, Beleigoli A, Gulyani A, Schultz T, Hines S, Clark RA, Hendriks. Effectiveness of nurse-led interventions versus usual care to manage hypertension and lifestyle behaviour: a systematic review and meta-analysis. JM.Eur J Cardiovasc Nurs. 2024 Jan 12;23(1):21-32. doi: 10.1093/eurjcn/zvad040.PMID: 37130339

3.       Presentation:  European Heart Rhythm Association (EHRA) Congress, 2023
Abstract: L Bulto, J Roseleur, S Noonan, A Pinero De Plaza, S Champion, H A Dafny, V Pearson, K Nesbitt, L Gebremichael, A Beleigoli, T Schultz, S Hines, R Clark, J Hendriks, Effectiveness of nurse-led interventions to manage hypertension and lifestyle behaviour effectively: a systematic review and meta-analysis, EP Europace, Volume 25, Issue Supplement_1, June 2023, euad122.763, https://doi.org/10.1093/europace/euad122.763

4.       Presentations: CSANZ Meeting, 2023
Abstract: L Bulto, J Roseleur, S Noonan, M Pinero de Plaza, S Champion, H Dafny, V Pearson, K Nesbitt, L Gebremichael, A Beleigoli, T Schultz, S Hines, R Clark, J Hendriks,
Nurse-Led Interventions Versus Usual Care to Manage Hypertension:: A Systematic Review and Meta-Analysis; Heart, Lung and Circulation, Volume 32, Issue, Suppl. 3, Pages S330

Awards:

Top Downloaded Paper award from European Society of Cardiology, EJCN
Listed most read article in the journal home page, since published
The evidence is used by others to inform nurse-led chronic disease management models and also received policy citation

Review 2 Lead: Dr Katie Nesbitt

5.       Katie Nesbitt, Lemlem Gebremichael, Alejandra Pinero de Plaza, Alline Beleigoli, Stephanie Champion, Robyn A Clark, Sonia Hines, Hendriks Jereon, Vincent Pearson. The effectiveness of interactive cardiac rehabilitation web applications versus usual care on program completion in patients with cardiovascular disease: A systematic review protocol. PROSPERO 2024 Available from https://www.crd.york.ac.uk/PROSPERO/view/CRD42021288690

6.       Nesbitt K, Champion S, Pearson V, Gebremichael LG, Dafny H, Ramos JS, Suebkinorn O, Pinero de Plaza MA, Gulyani A, Du H, Clark RA, Beleigoli A; NHMRC Country Heart Attack Prevention (CHAP) Partnership Project Team. The effectiveness of interactive cardiac rehabilitation web applications versus usual care on programme completion in patients with cardiovascular disease: A systematic review and meta-analysis of randomised controlled trials. J Telemed Telecare. 2023 Sep 28:1357633X231201874. doi: 10.1177/1357633X231201874. Online ahead of print. PMID: 37769293.

Award: Awarded European Journal of Cardiovascular Nursing Top 10 most downloaded papers 2022

Review 3 Lead: Ora Suebkinorn (PhD Candidate)

7.       Suebkinorn O, Ramos JS, Grace SL, Gebremichael LG, Bulamu N, Pinero de Plaza MA, Dafny HA, Pearson V, Hines S, Dalleck LC, Coombes JS, Hendriks JM, Clark RA, Beleigoli A. Effectiveness of alternative vs traditional exercises on cardiac rehabilitation program utilization in women with or at high risk of cardiovascular disease: a systematic review protocol. JBI Evid Synth. 2024 Feb 1;22(2):281-291. doi: 10.11124/JBIES-22-00394.PMID: 37435676

8.       Suebkinorn O, Ramos JS, Grace SL, Gebremichael LG,  Bulamu N, Pinero de Plaza MA, Dafny H, Pearson V, Hines S, Dalleck L, Coombes J, Hendriks JM, Clark RA, Beleigoli A. Effectiveness of alternative versus traditional forms of exercise on cardiac rehabilitation program utilization in women with or at high risk of cardiovascular disease: A systematic review protocol. PROSPERO 2024 Available from https://www.crd.york.ac.uk/PROSPERO/view/CRD42022354996

9.       Suebkinorn O, Ramos JS, Grace SL, Gebremichael LG, Bulamu N, Pinero de Plaza MA, Dafny HA, Pearson V, Hines S, Dalleck LC, Coombes JS, Hendriks JM, Clark RA, Beleigoli A. Effectiveness of alternative vs traditional exercises on cardiac rehabilitation program utilization in women with or at high risk of cardiovascular disease: a systematic review. JBI Evid Synth. 2025 (Accepted December 2024)

10.       Suebkinorn O, Ramos JS, Grace SL, Gebremichael LG, Bulamu N, Pinero de Plaza MA, Dafny HA, Pearson V, Hines S, Dalleck LC, Coombes JS, Hendriks JM, Clark RA, Beleigoli A. Effectiveness of alternative vs traditional exercises on cardiac rehabilitation program utilization in women with or at high risk of cardiovascular disease: a systematic review protocol. CSANZ ASM Brisbane August 12^th -17^th Abstracts Heart Lung Circulation 2025.

Review 4 Lead: Dr Maria Alejandra Pinero de Plaza

11.   Piñero de Plaza MA, Beleigoli A, Brown S, Bulto LN, Gebremichael LG, Nesbitt K, Tieu M, Pearson V, Noonan S, McMillan P, Clark RA, Hines S, Kitson A, Champion S, Dafny H, Hendriks JM. Effectiveness of telehealth versus standard care on health care utilization, health-related quality of life, and well-being in homebound populations: a systematic review protocol. Published: November 2022 in JBI Evidence Synthesis DOI: 10.11124/JBIES-21-00410 PubMed: 35975313

12.   Effectiveness of telehealth versus standard care on healthcare utilization, health-related quality of life and wellbeing in homebound populations: a systematic review protocol PROSPERO ID: CRD42021289578 Registration Date: 14 December 2021 Link: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=2895784

13.   Telehealth as a Care Solution for Homebound People: Systematic Review and Meta-Analysis of Healthcare Utilisation, Quality of Life, and Well-being Outcomes Status: Under major revision with Health & Social Care in the Community Original Submission Date: 29 February 2024 Reviewer Feedback Received: 11 April 2025

 Presentations / Awards / Media:

Presentation 1: Telehealth as a New Model of Care for Frail, Homebound and Bedridden People (FHBP)
Event: 2024 Annual General Meeting and Seminar
Date: 14 September 2024
Host: ME/CFS and FM Association of South Australia (ME Group Australia)
Presenter: Dr Maria Alejandra Piñero de Plaza
YouTube Recording: Watch (15:46 min)

Presentation 2: Transforming Healthcare for Frail, Homebound, and Bedridden People
Premiered: 12 March 2025
Platform: YouTube, Channel: Dr Maria Alejandra Piñero de Plaza, PhD
Views (as of April 2025): 109 YouTube Link: Watch here

Healthcare Innovator Award 2024 – Women of Colour in STEM Awards (5 Dec 2024, Melbourne)
National award recognising Dr Piñero de Plaza’s work on PROLIFERATE_AI, CR4ALL, and CLCT frameworks, and healthcare equity innovations.
Award link - Vice-President & Executive Dean’s Award 2021 – Research (Early Career) – Flinders University (14 Dec 2021)
Award link - Vice-President & Executive Dean’s Award 2022 – Research (Early Career) – Flinders University (13 Dec 2022)
Award link - Media & Public Engagement: Highlighting the Unseen campaign, ME Group Australia, advocating Medicare-funded telehealth for homebound populations IOS Press Chapter: Big data epidemiology study on FHBP in Studies in Health Technology and Informatics (2024) Read here -ResearchNow Profile – Dr Pinero de Plaza

Review 5 Lead: Dr Maria Alejandra Pinero de Plaza

14.   Pinero de Plaza, Maria Alejandra; Brown, Shannon; Wu, Chiung-Jung (Jo); Robyn, Clark,; McBride, Katharine; Gebremichael, Lemlem; et al. (2022). System enablers and barriers to continuity of care for First Nations people living with chronic conditions: A rapid qualitative review protocol. figshare. Online resource. https://doi.org/10.6084/m9.figshare.20310117.v2

15.   System enablers and barriers to continuity of care for First Nations people living with chronic conditions: a rapid qualitative review protocol PROSPERO ID: CRD42022339990 Link: https://www.crd.york.ac.uk/PROSPERO/view/CRD42022339990

16.   Pinero de Plaza Maria Alejandra Pinero, Lemlem Gebremichael, Shannon Brown, Chiung-Jung Wu, Robyn A. Clark, Katharine McBride, Sonia Hines, Odette Pearson, and Kim Morey. "Health system enablers and barriers to continuity of care for first nations peoples living with chronic disease." International journal of integrated care 23, no. 4 (2023): 17. https://doi.org/10.5334/ijic.7643

Presentations / Awards / Media:

An extended report version of the findings was shared confidentially with the South Australian Department for Health and Wellbeing, the Aboriginal Health Research Consortium, and SAHMRI to contribute to Closing the Gap policy and planning initiatives. - Featured in the Australian Indigenous HealthInfoNet Health Bulletin (updated 19 December 2023).

Decision‑Making Matrix to Co‑design Evidence‑Based Care Solutions with First Nations Peoples Published: 2023 by Flinders University DOI: https://doi.org/10.25451/flinders.24104940.v1  Media and Metrics: - Citations: 2 - Captures: 62 (Mendeley)

News Mentions: 1 News Coverage: Title: Research from Flinders University Yields New Findings on Chronic Disease Source: Insurance Daily News Date: 26 January 2024.

Media/Video: Improving Continuity of Care for First Nations Peoples – A Call to Action
Platform: YouTube Link: https://www.youtube.com/watch?v=O3d0g4FKnP4&t=4s

Review 6 Lead: Dr Norma Bulamu

17.   Bulamu NB, Hines S, Gebremichael LG, Mpundu-Kaambwa C, de Plaza MAP, Dafny HA, et al. Measurement properties of utility-based health-related quality-of-life measures in cardiac rehabilitation: a systematic review protocol. JBI Evid Synth. 2023;21(10):2082–91.

18.   Bulamu NB, Hines S, Gebremichael LG, Mpundu-Kaambwa C, de Plaza MAP, Dafny HA, et al. Measurement properties of utility-based health-related quality-of-life measures in cardiac rehabilitation: a systematic review protocol. Rregistered in PROSPERO on 27 July 2022. Registration number CRD42022349395

19.   Bulamu, N., C. Mpundu-Kaambwa, L. Gebremichael, M.A. Pinero de Plaza, H. Dafny, S. Hines, A. Beleigoli, B. Kaambwa, and R.A. Clark, and on behalf of the NHMRC CHAP Partnership Project Team "Measurement Properties of Utility-Based Quality of Life Measures Used in Cardiac Rehabilitation: A Systematic Review" Springer Nature Quality of Life Research. 2024 Vol 33: 2299-2320. https://doi.org/10.1007/s11136-024-03657-5

Review 7 Lead: Dr Lemlem Gebremichael

20.   Gebremichael, L., A. Beleigoli, S. Champion, K. Nesbitt, L. Bulto, M.A. Pinero de Plaza, V. Pearson, S. Noonan, J. Hendriks, R.A. Clark. "Effectiveness of Cardiac Rehabilitation Programs Versus Standard Care on Medication Adherence in Patients with Cardiovascular Disease: A Systematic Review Protocol." JBI Evid Synth. (11 Jul 2022). https://doi.org/10.11124/JBIES-21-00457

21.   Gebremichael, L., Champion, S., Nesbitt, K., Beleigoli, A., Bulto, L., Pinero de Plaza, M. A., Pearson, V., Noonan, S., Hendriks, J. & Clark, R., Effectiveness of cardiac rehabilitation programs vs standard care on medication adherence in eligible cardiovascular disease patients: a systematic review protocol. 11 Nov 2021, In: Prospero: International Prospective Register of Systematic Reviews. CRD42021284705 Available https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021284705

22.   Gebremichael LG, Champion S, Nesbitt K, Pearson V, Bulamu NB, Dafny HA, Sajeev S, Pinero de Plaza MA, Ramos JS, Suebkinorn O, Gulyani A, Bulto LN, Beleigoli A, Hendriks JM, Hines S, Clark RA; NHMRC CHAP Project Team. Effectiveness of cardiac rehabilitation programs on medication adherence in patients with cardiovascular disease: A systematic review and meta-analysis. Int J Cardiol Cardiovasc Risk Prev. 2023 Dec 12;20:200229. doi: 10.1016/j.ijcrp.2023.200229. eCollection 2024 Mar.PMID: 38188637 Free PMC article.

Review 8 Lead: Trophy Chen (PhD Candidate)

23. Chen RT, Pearson V, Suebkinorn O, et al. Effectiveness of receiving cardiovascular disease genetic risk information on health behaviors, psychological responses, and associated risk factor modification in individuals: a systematic review protocol. JBI Evidence Synthesis. 2024;22(12)

24. Chen RT, Pearson V, Suebkinorn O, et al. Effectiveness of receiving cardiovascular disease genetic risk information on health behaviors, psychological responses, and associated risk factor modification in individuals: a systematic review protocol. PROSPERO 2024 Registration no. CRD42023434372

25. Chen RT, Pearson V, Suebkinorn O, Bulto LN, Anderson A, Nelson AJ, et al. Impact of genetic risk information for cardiovascular disease on behavioural changes, psychological responses and risk factor modification: a systematic review. Eur J Prev Cardiol [Internet]. 2024;1–11. Available from: https://doi.org/10.1093/eurjpc/zwae362

26. Chen RT, Pearson V, Suebkinorn O, et al. Impact of Receiving Genetic Risk Information for Cardiovascular Disease on Risk Factor Modification, and Associated Behavioural and Psychological Behaviours: A Systematic Review and Meta-Analysis. Heart Lung Circ. 2024;33:S313. doi:10.1016/j.hlc.2024.06.406

Presentations / Awards:

Chen, RT., Pearson, V., Suebkinorn, O., Bulto, L. N., Pincha Baduge, M., Anderson, A., Nelson, A. J., Zoungas, S., Clark, R. A., & Nicholls, S. J. (2024). Impact of receiving genetic risk information for cardiovascular disease on risk factor modification, and associated behavioural and psychological behaviours: a systematic review and meta-analysis. Poster presentation at the ISONG Annual Scientific Meeting, San Diego, the United States, November 2024

Chen, RT., Pearson, V., Suebkinorn, O., Bulto, L. N., Pincha Baduge, M., Anderson, A., Nelson, A. J., Zoungas, S., Clark, R. A., & Nicholls, S. J. (2024). Impact of receiving genetic risk information for cardiovascular disease on risk factor modification, and associated behavioural and psychological behaviours: a systematic review and meta-analysis. Poster presentation at the CSANZ/ANZET Annual Scientific Meeting, Perth Convention Centre, Western Australia, August 2024

Chen, RT., Pearson, V., Suebkinorn, O., Bulto, L. N., Pincha Baduge, M., Anderson, A., Nelson, A. J., Zoungas, S., Clark, R. A., & Nicholls, S. J. (2024). Impact of receiving genetic risk information for cardiovascular disease on risk factor modification and associated behavioural and psychological behaviours: a systematic review and meta-analysis.

Poster presentation at the ISONG Annual Scientific Meeting, San Diego, the United States, November 2024 – 3^rd Prize

Review 9 Lead: Trophy Chen (PhD Candidate)

27. Chen RT, Nelson AJ, Tan S, Clark RA, Zoungas S, Nicholls SJ. The effectiveness of visualising plaque on cardiac computed tomography in modifying risk factors for cardiovascular disease: A systematic review protocol. PROSPERO 2024 Registration No. CRD42023390876

28. Chen RT, Nelson AJ, Tan S, Clark RA, Zoungas S, Nicholls SJ. The effectiveness of visualising plaque on cardiac computed tomography in modifying risk factors for cardiovascular disease: A systematic review. J Cardiovasc Comput Tomogr [Internet]. 2024;18(3):223–32. Available from: https://doi.org/10.1016/j.jcct.2024.02.007

Presentation /Awards:

Chen, RT., Nelson, A. J., Tan, S., Clark, R. A., Zoungas, S., & Nicholls, S. J. (2023). Cardiac Computed Tomography to Visualise Plaque and Modify Risk Factors: A Structured Review of the Evidence. Poster presentation at the CSANZ/ANZET Annual Scientific Meeting, Adelaide Convention Centre, South Australia, August 2023

Review 10 Lead: Dr Hila Dafny

29.   Dafny HA, Champion S, Gebremichael LG, Pearson V, Nesbitt K, Pinero De Plaza MA, et al. Effectiveness of activity-monitoring devices in patients with cardiovascular disease participating in cardiac rehabilitation programs: an umbrella review protocol. JBI Evid Synth. 2022;20(11):2806–14.

30.   Dafny, H., S. Champion, L. Gebremichael, V. Pearson, K. Nesbitt, M.A. Pinero de Plaza, L. Bulto, S. Noonan, S. Hines, J. Hendriks, R.A. Clark, and A. Beleigoli. "Effectiveness of Using Activity Monitoring Devices and Mobile Applications Versus Standard Care on Physical Activity and Health Outcomes of Patients with Cardiovascular Disease Participating in Cardiac Rehabilitation Programs: An Umbrella Review." PROSPERO  (10 Jan 2022). https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022298877 

31.   Dafny, H., S. Champion, L. Gebremichael, V. Pearson, J. Hendriks, R.A Clark, M.A. Pinero de Plaza, A. Gulyani, S. Hines, A. Beleigoli. “Cardiac rehabilitation, physical activity, and the effectiveness of activity monitoring devices on cardiovascular patients: an umbrella review of systematic reviews”. European Heart Journal - Quality of Care and Clinical Outcomes, qcad005 (23 Jan 2023). https://doi.org/10.1093/ehjqcco/qcad005

Awards: Cited 14 times and had a total view of 2,856 (with 1,027 PDF downloads), as you can see in the metrics below. We also received recognition of our UR paper’s impact, as seen in the attached document.

Review 11 Co-reviewer: Dr Alline Beleigoli

32.   Inglis, S.C., R.A. Clark, S. Allida, R. Prichard, A. Beleigoli, A. Laconelli, P. Pellicori, and J. Cleland. "Structured Telephone Support or Non‐Invasive Telemonitoring for Patients with Heart Failure."  2025 ( For submission to Cochrane 2025)